The upregulated genes in LP-HF included several genes associated with lipid localization and transport, such as ATP-binding cassette, subfamily A, member 1 (Abca1), high-density lipoprotein binding protein (Hdlbp), oxysterol binding protein-like 9 (Osbpl9), phosphatidylinositol transfer protein, cytoplasmic 1 (Pitpnc1). The gene discussed is OSBPL9; the disease is hydrops fetalis.