LRRK2-PD mutants with decreased phosphorylation of Ser910 and Ser935 (predominantly species with mutations in the Roc-COR domain) show reduced affinity for 14-3-3 proteins (Li et al., 2011; Muda et al., 2014; Nichols et al., 2010). This evidence concerns the gene LRRK2 and Parkinson disease.