Interestingly, the upregulation of glucose transporter 1 (GLUT1) and glucose transporter 3 (GLUT3) in mammalian cells during Chlamydia infection is dependent on Chlamydia-induced MAPK kinase activation [60], suggesting that Chlamydia survival depends on the MAPK signaling pathway. The gene discussed is SLC2A1; the disease is chlamydia infectious disease.