Additionally, ageing-derived risk score presented negative correlations to activities of CD8+ T effector, pan-F-TBRS, antigen processing machinery, and FGFR3-related genes but had positive correlations to activities of DNA damage repair, Fanconi anemia, cell cycle, DNA replication, nucleotide excision repair, homologous recombination, mismatch repair, and cell cycle regulators (Figure 7E). Here, CD8A is linked to Fanconi anemia.