CD8A and Fanconi anemia: In Figure 3A, C1 presented increased activities of CD8+ T effector, DNA damage repair, antigen processing machinery, immune checkpoint, KEGG discovered histones, Fanconi anemia, cell cycle, DNA replication, nucleotide excision repair, homologous recombination, mismatch repair, and cell cycle regulators compared with C2 and C3, indicative of immune and tumorigenic activation in C1.