MAST1, PRDM14, and ZNF177 irregular DNA methylation variants were found and verified as prospective breast cancer molecular indicators by X Mao et al. X Mao et al. also showed that the DNA methylation range of ADCY4, CPXM1, DNM3, PRDM14, PRKCB, and ZNF177. Here, ADCY4 is linked to breast carcinoma.