STING1 and colonic neoplasm: In addition, ADU-S100, one of promising agonists of STING, exhibits significant inhibition on colon tumor and ascites in the case of synergistically cooperating with anti-PD-1 and anti-COX2 (Lee et al., 2021), which is investigated in clinical phase I trials of solid tumors and lymphomas (Sivick et al., 2018; Meric-Bernstam et al., 2021).