Herein, we applied stepwise regression analysis to compose a clinical prognostic signature for BLCA patients with 13 IMRGs (TCIRG1, CTSE, ATP6V0A1, CYP2C8, RNF19A, CYP4Z1, YPEL5, PLOD1, BMP6, CAST, SCD, IFNG, and ASIC3). Here, BMP6 is linked to bladder transitional cell carcinoma.