CEP290 and Abnormal retinal morphology: In their experiments, they successfully delivered multiple AAV vectors, each encoding one of the fragments of target proteins flanked by the split intein, and reconstituted the large ATP binding cassette subfamily A member 4 (ABCA4) as well as centrosomal protein 290 (CEP290) in the retina of mice, pigs and in human retinal organoids to cure the inherited retinal diseases (Tornabene et al., 2019).