GZMB and hepatitis B virus infection: Taken together, our gene expression analysis of PBMCs from hepatitis B related HCC patients has demonstrated the presence of alterations, and additional qRT-PCR verification and receiver operating characteristic curve analysis have revealed that seven genes are differentially expressed in the patients with HCC (TYMP, TYROBP, CD14, TGFBI, LILRA2, GNLY, and GZMB).