Recently, several different biomarkers, including CXCR2, CCR2, EP400, SELENBP1, SLC4A1, SLC26A8, HSPA8P4, CALM1, RPL7p24, FLNA, and CLU have been reported to be associated with the progression of HCC [25, 27, 32]. Here, EP400 is linked to hepatocellular carcinoma.