IFNGR1 and chronic hepatitis B virus infection: miR-548ah-5p is up-regulated at the immune activation phase of chronic hepatitis B patients, and in vitro studies using THP-1 cells treated with miR-548ah-5p mimics suggest that it may involve the reduced expression of IFN-γR1, which may, in turn, facilitate viral pathogenesis (Xing et al., 2014).