The expression is significantly reduced in cancers such as gastric cancer (36), cervical cancer (37), and esophageal cancer (38).Numerous studies have shown that PPARγ has antitumor effects on lung cancer, breast cancer, prostate cancer and colon cancer (39), which undoubtedly provides a new direction for the treatment of colon cancer. The gene discussed is PPARG; the disease is malignant colon neoplasm.