PIK3CA and colorectal carcinoma: Last, we exhibited the top 10 mutated FRGs in CRC with ranked percentages, including TP53 (58%), KRAS (45%), PIK3CA (30%), FBXW7 (17%), ATM (14%), MYOR (10%), SETD1B (8%), SKC3A2 (8%), ACVR1B (6%), and DUOX2 (5%) (Figure 11B).