Of note, MA showed a potent hypoglycaemic effect and was able to prevent renal, cardiac, and hepatic damage in streptozotocin (STZ)-induced T1DM in rats, by suppressing ROS and concomitant upregulation of the antioxidant enzymes, superoxide dismutase (SOD), and glutathione peroxidase (GPX) [34]. This evidence concerns the gene SOD1 and type 1 diabetes mellitus.