As shown in Figure 5B, IL-3Rα was strongly expressed and co-localized with Iba-1 surrounding amyloid plaques in both the cortex (Small: P < 0.001; Medium: P = 0.001; Large: P < 0.001) and hippocampus (Small: P < 0.001; Medium: P < 0.001; Large: P < 0.001) of AD animals with PBM treatment. The gene discussed is AIF1; the disease is Alzheimer disease.