IL4 and Alzheimer disease: Furthermore, the anti-inflammatory cytokines (IL-4, IL-10, and IL-13) were significantly elevated in the cortex and hippocampus of AD rats rats (Cortex-IL-4: P = 0.0054; Hippocampus-IL-4: P = 0.0001; Cortex-IL-10: P = 0.0004; Hippocampus-IL-10: P < 0.001; Cortex-IL-13: P = 0.0005; Hippocampus-IL-13: P < 0.001), and PBM treatment further enhanced the levels of these anti-inflammatory cytokines (Cortex-IL-4: P = 0.0007; Hippocampus-IL-4: P = 0.0002; Cortex-IL-10: P = 0.0004; Hippocampus-IL-10: P = 0.025; Cortex-IL-13: P = 0.0054; Hippocampus-IL-13: P = 0.0068).