As shown in Figure 2A, MBP staining showed AD rats had significantly decreased MBP intensity in both the cortex (P = 0.00136) and hippocampus (P < 0.001), which was significantly reversed in PBM-treated AD rats (Cortex: P = 0.0443; Hippocampus: P = 0.0005). Here, MBP is linked to Alzheimer disease.