lnc7514 and lncagf expression levels did not differ in SLE patients and healthy controls, further research on the relationship between clinical symptoms and laboratory test results in SLE patients found that the expression level of lnc7514 decreased in patients with anti-dsDNA and lnc7514 was inversely associated with ESR, CRP, and SLEDAI, suggesting that lnc7514 may be related to the occurrence of SLE inflammation and disease activity. The gene discussed is CRP; the disease is systemic lupus erythematosus.