We noticed that the behaviors of MMP12 were distinctly enhanced on ESCC specimens comparing to nontumor specimens, including MMP1 (Figure 1(b)), MMP3 (Figure 1(c)), MMP7 (Figure 1(d)), MMP8 (Figure 1(e)), MMP9 (Figure 1(f)), MMP13 (Figure 1(g)), MMP10 (Figure 1(h)), MMP11 (Figure 1(i)), MMP12 (Figure 1(j)), MMP14 (Figure 1(k)), MMP17 (Figure 1(l)), and MMP20 (Figure 1(m)). This evidence concerns the gene MMP7 and esophageal squamous cell carcinoma.