Human epidermal growth factor receptor 2 (HER2), alias Neu or ErbB2, is an important oncogene that has an essential function in cell proliferation and dedifferentiation (Yarden and Sliwkowski, 2001) and has also been extensively studied in breast (Slamon et al., 2001; Slamon et al., 2011), gastric (Bang et al., 2010), and colon cancer (El-Deiry et al., 2015). The gene discussed is ERBB2; the disease is malignant colon neoplasm.