CD4 and neoplasm: As for the relationship between CLCF1 expression and tumor-infiltrating immune cells (TIICs), We compared the analytical results of TCGA (Figure 6B) and CGGA (Supplementary Figure S8A) and found a similar statistically significant difference in the distribution of plasma cells, CD8+ T cells, naïve CD4+ T cells, activated memory CD4+ T cells, T regulatory cells (Tregs)(Supplementary Figure S8E), gamma-delta T cells, monocytes, M0 macrophages, and M1 macrophages.