IL6 and metabolic dysfunction-associated steatotic liver disease: The GO analysis of BP revealed that cytokine production and secretion, protein secretion, and regulation of hormone level were increased (Figure 3B), suggesting that a crosstalk between the muscle and the metabolic organs happened in NAFLD, consistent with a previous finding that blocking cytokines, such as IL6, in NAFLD mice could alleviate insulin resistance in the skeletal muscle (30, 31).