Inhibition of TACE (↓ neutrophil accumulation in the alveolar space, ↓ ICAM-1, ↓ MCP-1, ↓ CINC, ↓ HMGB1, and ↓ soluble epithelial cadherin and ↓ neutrophil elastase activity in BALF, ↓ endothelial and alveolar septal damage, ↓ transplantation-related ALI). This evidence concerns the gene CDH1 and acute respiratory distress syndrome.