INS and age-related macular degeneration: Accordingly, previous studies of oral antidiabetics and insulin have also been proposed for the treatment of glaucoma as well as other ocular conditions such as age-related macular degeneration (AMD) (Ott et al., 2014; Lin et al., 2015, 2017; Chung et al., 2016, 2019; Maleškić et al., 2017; Douros et al., 2018; Kim et al., 2018; Li et al., 2018; Vilsbøll et al., 2018; Wang et al., 2018; Brown et al., 2019; Chen et al., 2019; Fan et al., 2020; Gaborit et al., 2020; Blitzer et al., 2021; Sterling et al., 2021).