In contrast, the downregulation of RANTES/CCL5, MIP-1α/CCL3, and MIP-1β/CCL4 from the early to middle phase of the infection as well as the downregulation of MIG/CXCL9, IP-10/CXCL10, and IL-13 in the middle phase of the infection were observed in aged BALB/c mice. Here, CCL5 is linked to infection.