Kaplan–Meier analysis revealed that ICC samples with high WWP1 expression had shorter overall survival (OS) (Fig. 1F) and higher recurrence (Fig. 1G) than ICC samples with low WWP1 expression (25.36 vs. 54.99%, OS; 17.74 vs. 35.92%, DFS; both P < 0.05). The gene discussed is WWP1; the disease is intrahepatic cholangiocarcinoma.