DGAT1 and colonic neoplasm: For example, taxifolin inhibits diacylglycerol acyltransferase (DGAT) and microsomal triglyceride transfer protein (MTP) activity in human hepatocellular carcinoma (HepG2) cells, thus exerting an antihepatocarcinogenic effect; it also has a significant inhibitory effect on the colony-forming ability of HCT-116 human colon cancer cells [36, 37].