IL5 and chronic rhinosinusitis with nasal polyps: Furthermore, another study isolated Dispersed Nasal Polyp Cells (DNPCs) from CRSwNP patients and cultured them with SEB and fungal extracts from Candida, Aspergillus, and Alternaria. A significantly higher expression of IL-5, IL-13, and RANTES was detected in DNPCs after exposure to SEB compared to the fungal extract.