Gastrodin ameliorated histopathological lesions of hepatocytes, alleviated liver inflammation and reduced the level of cytokines and chemokines, such as TNF‐α, IFN‐γ and IL‐6, chemokine (C‐X‐C motif) ligand 1 (CXCL‐1), vascular cell adhesion molecule 1 (VCAM‐1) in a dose‐dependent manner by regulating the NF‐κB and AMPK/Nrf2 pathways in alcohol‐induced AIH.78 The gene discussed is TNF; the disease is autoimmune hepatitis.