ASCL1 is a transcription factor required for the proper development of pulmonary neuroendocrine cells (Augustyn et al, 2014) while NEUROD1 is a neuronal/neuroendocrine protein that helps migration and survival of neuroendocrine carcinomas (Osborne et al, 2013). The gene discussed is NEUROD1; the disease is neuroendocrine carcinoma.