In this regard, BAX, another member of the BCL2 gene family, immunolocalizes in lysosomes in a variety of cell lines exposed to pro‐apoptotic stimuli (Feldstein et al., 2006; Oberle et al., 2010; Werneburg et al., 2007) and in experimental models of Parkinson's disease (Bove et al., 2014), where it has been shown to induce lysosomal membrane permeabilization and lysosomal dysfunction. This evidence concerns the gene BAX and Parkinson disease.