TARDBP and neurodegenerative disease: We chose to focus on these specific proteins based on their known and distinct roles in post-transcriptional regulation in the nervous system and because of TDP-43’s importance in neurodegenerative diseases that affect cortical neurons (Buratti and Baralle, 2014; Goldstrohm et al., 2018; Lagier-Tourenne et al., 2010; Martínez et al., 2019; Vessey et al., 2012; Zahr et al., 2018; Zhang et al., 2017).