DRD2 and Parkinson disease: Such α‐Syn‐mediated disruption of DRD2 anti‐inflammatory effect was carried out by inhibiting the association of β‐arrestin‐2 with transforming growth factor‐beta‐activated kinase 1 (TAK1)‐binding protein 1 (TAB1) and promoting TAK1‐TAB1 interaction in astrocytes, underscoring the ability α‐Syn disrupts the function of β‐arrestin‐2 and inflammatory pathways in the pathogenesis of PD (Du et al., 2018).