However, in October 2020, Leisman et al. suggested that role of cytokine release syndrome is questionable in the etiopathogenesis of severe or critical cases of COVID-19 as mean IL-6 in these conditions were significantly lower as compared to that in other inflammatory syndromes such as Sepsis, ARDS and CAR Tcell induced cytokine release syndrome (Leisman et al. 2020). Here, IL6 is linked to Sepsis.