CTSD and infection: From the early response of M2e-specific Trm cells to the recovery phase of infection on day 8 there was a shared increase in expression of adaptive anti-viral response genes (Nkg7, Ccl5, Ctsd, Ctsw) and lymphocyte activation and maturation-associated genes (Icos, Jak3, Id2, Ramp1, Maf, Lgals1, Lgals3) as well as genes linked to cell motility (Cxcr6, Ccr2, Itgb2, Lsp1, Glrx)(Fig. 3e, Supplementary Fig. S5b).