PDGFRB and colorectal carcinoma: DNA was extracted from multiple normal tissue samples (multiple buccal swabs, urothelial cells from urine samples, normal colonic mucosa adjacent to CRC, normal colonic mucosa distant from the CRC, normal gastric mucosa) and subjected to ultradeep sequencing with the OCAv3 panel (mean read-depth across samples 15000X) allowing the potential detection of the PDGFRB and the BRCA1 shared variants.