ACE2 and COVID-19: Given the current scenario where individual risk factors for severe COVID-19 disease still remain unclear, this cross-sectional observational study aimed to determine the expression of ACE2 in the lung parenchyma of post-mortem tissue from fatal COVID-19 cases in relation to histopathology, markers of vascular and inflammatory responses, and clinical features in order to ascertain its role, if any, in disease severity and potential for therapeutic targeting.