It was also reported that Ras GTPase-activating protein-binding protein 1 (G3BP1), one of the important components of stress granules (SGs), could be regulated by YB1 in human sarcomas, and YB1 could directly bind to and translationally activate the 5' untranslated region (UTR) of G3BP1 mRNAs, thereby controlling the formation of SGs13. This evidence concerns the gene YBX1 and sarcoma.