YBX1 and nasopharyngeal carcinoma: In this study, we analyze the mRNA expression and potential clinical significance of YBX1 in patients with head and neck squamous carcinoma (HNSC) and NPC in TCGA database and GEO database respectively, also detected the expression of YB1 proteins in NPC tissues and control nasopharyngeal epithelial tissues by immunohistochemistry (IHC), seeking the relationship between expression of YB1 and clinicopathological features and their potential prognostic significance in NPC patients.