In a cohort of 43 Japanese CD/CRD patients analyzed using an NGS exome-sequencing panel targeting 193 known inherited eye disease genes, genetic diagnoses were made in 12 (27.9%) patients, and ABCA4 was the most representative mutated gene (9.3%, 4/43 of the total cohort; 33.3%, 4/12 of solved cases)30. This evidence concerns the gene ABCA4 and eye disorder.