We also found several previously unknown predictive biomarkers, including Kruppel like factor 9 (KLF9),60 Poly (ADP-Ribose) polymerase family member 3 (PARP3),61 and Podocalyxin like 2 (PODXL2);62 none of these have been previously associated with tumor drug resistance or reported as predictive biomarkers for targeted therapies. The gene discussed is KLF9; the disease is neoplasm.