For these recommendations, it was agreed to define clear ‘on-target’ SDHA-associated tumours based on published literature and expert group opinion to make practical recommendations regarding reporting, clinical management and predictive testing (the terms on-target and SDHA-associated tumours are synonymous, but the term SDHA associated has been used through this document).4 13–15 Tumours not specifically listed in this table are currently considered to be ‘off-target’ tumours (table 1). The gene discussed is SDHA; the disease is neoplasm.