A case-control study in Japanese population [24] reported the EAAT2 gene polymorphism was associated with schizophrenia, and concluded that at least one of the susceptibility locus for schizophrenia may reside in internal or nearby EAAT2. In contrast, no association was observed between the polymorphism − 181 A/C (rs4354668) in SLC1A2 (EAAT2) and onset of schizophrenia and its psychopathology in Polish population [37]. This evidence concerns the gene SLC1A2 and schizophrenia.