TMEM43 and familial pancreatic carcinoma: The results found that patients with pancreatic cancer in TMA cohort 2 (p = 0.0354, Fig. 1D) with a high expression level of TMEM43 had worse OS, and patients in the cancer Genome Atlas (TCGA) database with a high expression level of TMEM43 had worse OS (p = 0.0092) and DFS (p = 0.0003) (Fig. 1E, F).