To further confirm this result in vivo, intratumoral injection of live bacteria was performed according to the recent studies.27,28 We found that intratumoral injection of live L. paracasei sh2020 also considerably prevented tumor growth (Figure 7f-g), induced CXCL10 expression, and CD8+ T cell infiltration in the tumor beds (Figure 7h-i). The gene discussed is CD8A; the disease is neoplasm.