Considering two groups of our patients based on clinical NCI CTCEA scale, mild neuropathy (grade 1) in contrast to severe (grade 2 and 3), no statistically significant differences were found for neurophysiological (SNAP amplitude), psychophysical (TST abnormalities) or histological (IENFD-ir PGP 9.5 or GAP-43 fibers) data. This evidence concerns the gene GAP43 and neuropathy.