MCAM and diabetes mellitus: CD146 has also been reported to function in association with CD36, a multifunctional class B scavenger receptor.[19] CD36 is highly expressed on macrophages and adipocytes, implicating its role in the development of insulin resistance and diabetes.[57, 58] CD36 functions as a principal receptor for the uptake of long‐chain fatty acids and oxidized lipids, thereby leading to lipid loading and foam cell formation, and its internalization triggers inflammatory signaling cascades.