Furthermore, there was a trend toward higher mortality, higher need for invasive mechanical ventilation, higher serum inflammatory markers (CRP, ferritin, LDH, leukocytes) and serum D-dimer levels (a marker of thrombin generation and fibrinolysis related to endothelial damage) in the AKI-NRF group compared to the AKI-CKD group. Here, CRP is linked to chronic kidney disease.