Of note, no difference was appreciated in all the variables over time in the Group B patients, while among non-lymphopenic patients who showed a progression to lymphopenia, a statistically significant reduction was observed only for CD19+ cells (mean ± SD at diagnosis 248 ± 55 vs 86.6 ± 19.5 at Fup, P = 0.015). Here, CD19 is linked to lymphopenia.