A total of 2739 DEGs (|log2FC | ≥ 1 and FDR < 0.05), 1337 upregulated and 1402 downregulated, were detected between AML-IRF7−/−-c-kit+ and AML-WT-c-kit+ cells (Supplementary Fig. S5A). This evidence concerns the gene IRF7 and acute myeloid leukemia.