The mRNA expressions of TNF-α, IFN-γ, IL-4, and IL-17 were significantly higher in LPS-induced CRS mice (LPS + PBS) compared with those of control group mice, and these cytokines were significantly decreased by PVP-I (LPS + PVP-I) and dexamethasone (LPS + DEX) treatment (Fig. 7a). The gene discussed is TNF; the disease is congenital rubella syndrome.