PDPN and metastatic neoplasm: In both microscopic- and major-ENE, podoplanin expression and mean score were significantly higher in perinodal stroma than in intranodal metastatic tumor area (0.30 ± 0.675 vs. 2.00 ± 1.247; p = 0.001, 0.56 ± 1.042 vs. 1.83 ± 0.786, p < 0.001) (Supplementary table 1).