ANXA5 and diffuse large B-cell lymphoma: When the SC1 DLBCL cell line was treated with increasing doses of tamoxifen (10, 15, 20 μM) for 24 hours, the percentage annexin V/propidium iodide (PI) positive cells increased from 7.7% (control) to 13.5% (10 μM, P = 0.005), 31.7% (15 μM, P = 0.007), and 80.5% (20 μM, P = 0.003), respectively (Fig. 3A).