RNH1 and COVID-19: Furthermore, we identified decreased RNH1 protein expression in COVID-19 patients with severe symptoms admitted to the ICU compared with COVID-19 patients with less severe symptoms admitted to the general ward, suggesting that RNH1 expression may be negatively related to the severity of the COVID-19 disease, and this was confirmed in an independent cohort of patients with COVID-19 using postmortem lung tissue.