FOXP3 and rheumatoid arthritis: Recently, Ghoryani et al. [53] indicated that intravenous injection of 1 × 106 autologous BM-MSCs per kg into 13 patients with refractory RA significantly up-regulates the gene expression of forkhead box P3 (FOXP3) in peripheral blood mononuclear cells (PBMCs) after 1 year.